顱內壓無創綜合檢測分析儀在同一儀器平臺上綜合利用了基于閃光視覺誘發電位(FVEP)和經顱多普勒(TCD)的顱內壓無創檢測方法,與單一方法比較,具有較強的臨床適用性和檢測精度。
       閃光視覺誘發電位(FVEP)是一種皮層誘發電位,是指由彌散的非模式的光刺激后所引起的大腦皮層(枕葉)的電位變化。FVEP反映了從視網膜到枕葉層視通路的完整性。視覺通路位于腦底部,行程較長,顱內壓增高對腦干產生機械壓迫,腦干血管變壓,循環發生障礙,神經元及纖維缺血缺氧,代謝出現障礙,神經電信號傳導阻滯,FVEP波峰潛伏期延長,波幅下降,波寬加大,當腦疝形成時則較為明顯。這樣通過建立FVEP與ICP之間的回歸方程,可通過檢測FVEP來推算ICP。
       顱內壓主要來自心臟周期波動以及受呼吸運動的影響導致的腦血流波動產生的壓力,其波形由脈沖波和呼吸波組成。而TCD是研究腦血流波動的,因此,顱內壓的波動與TCD研究的腦血流波動理論有密切的關系。

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